Review



ip 3 r agonist  (Sirius Fine Chemicals)


Bioz Verified Symbol Sirius Fine Chemicals is a verified supplier
Bioz Manufacturer Symbol Sirius Fine Chemicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    Sirius Fine Chemicals ip 3 r agonist
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ip 3 R Agonist, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 101 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc13024370-65-31-23?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 101 article reviews
    ip 3 r agonist - by Bioz Stars, 2026-08
    94/100 stars

    Images

    1) Product Images from "Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens"

    Article Title: Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens

    Journal: Antioxidants

    doi: 10.3390/antiox15030323

    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Figure Legend Snippet: Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Techniques Used: Staining, TUNEL Assay, Quantitative RT-PCR, Expressing, Western Blot, Control

    Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Figure Legend Snippet: Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Techniques Used: Quantitative RT-PCR, Expressing, Western Blot, Control



    Similar Products

    ip 3 r agonist  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals ip 3 r agonist
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ip 3 R Agonist, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc13024370-65-31-23?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    ip 3 r agonist - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    membrane permeant myo inositol 1 4 5 trisphosphate derivative  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals membrane permeant myo inositol 1 4 5 trisphosphate derivative
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Membrane Permeant Myo Inositol 1 4 5 Trisphosphate Derivative, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc13024370-65-14-23?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    membrane permeant myo inositol 1 4 5 trisphosphate derivative - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    caged ins 145 p3 pm  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals caged ins 145 p3 pm
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Caged Ins 145 P3 Pm, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/bio_rxiv__2025__11__06__687025-43-19-20?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    caged ins 145 p3 pm - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    ip3  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals ip3
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ip3, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/bio_rxiv__2025__09__16__676493-314-32-33?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    ip3 - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    ins 1 4 5 p3  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals ins 1 4 5 p3
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ins 1 4 5 P3, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc12243451-153-0-7?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    ins 1 4 5 p3 - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    ins 1 4 5 p  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals ins 1 4 5 p
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ins 1 4 5 P, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc12126608-82-3-16?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    ins 1 4 5 p - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    cag iso 2 145 10  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals cag iso 2 145 10
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Cag Iso 2 145 10, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc11540855-296-23-24?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    cag iso 2 145 10 - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    ip 3 analog ci ip  (Sirius Fine Chemicals)
    94
    Sirius Fine Chemicals ip 3 analog ci ip
    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
    Ip 3 Analog Ci Ip, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/caged+ins+phosphate/pmc12424127-75-10-18?v=Sirius+Fine+Chemicals
    Average 94 stars, based on 1 article reviews
    ip 3 analog ci ip - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Journal: Antioxidants

    Article Title: Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens

    doi: 10.3390/antiox15030323

    Figure Lengend Snippet: Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Article Snippet: SWFs were pretreated with a 10 μM concentration of AP for 24 h. A membrane-permeant myo-inositol-1,4,5-trisphosphate derivative (10 μM IP 3 /AM, CAT3-1-145, SiChem GmbH, Bremen, Germany) was employed as an IP 3 R agonist for the inositol 1,4,5-trisphosphate receptor (IP 3 R), a critical calcium release channel on the endoplasmic reticulum.

    Techniques: Staining, TUNEL Assay, Quantitative RT-PCR, Expressing, Western Blot, Control

    Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Journal: Antioxidants

    Article Title: Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens

    doi: 10.3390/antiox15030323

    Figure Lengend Snippet: Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

    Article Snippet: SWFs were pretreated with a 10 μM concentration of AP for 24 h. A membrane-permeant myo-inositol-1,4,5-trisphosphate derivative (10 μM IP 3 /AM, CAT3-1-145, SiChem GmbH, Bremen, Germany) was employed as an IP 3 R agonist for the inositol 1,4,5-trisphosphate receptor (IP 3 R), a critical calcium release channel on the endoplasmic reticulum.

    Techniques: Quantitative RT-PCR, Expressing, Western Blot, Control